Nano Biomedicine
ORIGINAL ARTICLE

Behavior of Trace Elements in Novel Apatite-ionomer Cement

Hsiu-Hui CHIU1, Yukari SHINONAGA2, Takako NISHIMURA2, Kyoko HARADA2, and Kenji ARITA2

1Graduate School of Dentistry (Department of Pediatric Dentistry),
2Department of Pediatric Dentistry,
Osaka Dental University, Osaka, Japan


Nano Biomed 2016;8(2):101-111, (Dec 30, Nano Biomedicine)

Synopsis
The present study investigated the role of matrix on the behavior of elements in HAp-added con-ventional glass ionomer cement (GIC), referred to as gapatite-ionomer cement (AIC)." The AIC samples were produced by replacing 8-16 wt% of GIC powder with porous spherical-shaped HAp. One-half of the samples had the matrix-rich layer removed. The AIC and GIC samples with and without a matrix-rich layer underwent multi-element analysis using a fluoride electrode and ICP-AES. The antibacterial activity of the samples against S. mutans was also evaluated using ATP-luminescence methods. The mineral ion release properties and antibacterial activity of AICs were superior to those of GIC. The concentrations of elements released from GIC and AIC samples with a matrix-rich layer were significantly greater than those from GIC and AIC samples without the matrix-rich layer. The luminescence intensities of S. mutans suspensions containing immersed AICs were significantly lower than those of suspensions containing GIC.

Key words: glass ionomer cement, hydroxyapatite, fluoride release, elemental analysis, antibacterial test

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